The ingredients in this product contain flavonoids that possess anti-oxidative, anti-tumorigenic, anti-inflammatory, anti-bacterial, anti-angiogenic, anti-cancer anti-oncogene, and immunostimulating properties.
This product acts as a natural antihistamine by preventing mast cell degranulation. It attenuates airway mucus production by inhibiting gamma-aminobutyric Acid (GABAA) receptors. It decreases inflammation by modulating immune cytokines.
A tumor is an abnormal group of cells. A tumor forms when the DNA gets damaged. Cells grow and divide as a part of the body’s natural process, when the Tumor Suppressing Gene (TSG) gets damaged, (TSG is a gene that regulates a cell during cell division and replication.), it damages nearby cells resulting in cell mutation.
One of the ways this product work is by activating the DNA damage response (DDR). A signaling pathway in which ATM/ATR Kinases block cell-cycle progression through stabilization of P53 (tumor protein).
TSG repairs DNA, it tells cells when to die. When the TSG is mutated, it results in a loss of reduction in its function. The
How Does This Product Work?
This product inhibits the proliferation of human chronic myelogenous leukemia k562 cells. By activating the apoptotic processes via caspase-3 overexpression and the regulation of the NF-k3 and MAPK signaling. The activation to the nuclear factor-kB (NF-KB) plays a vital role in regulating the pathological changes during tumor progression from cellular proliferation to the invasion of the organs.
The suppression of the NF-kB transcription factor activation is involved in inhibiting tumor cell growth by inducing apoptosis.
This product can help target multiple biochemical and molecular pathways. It helps to target multiple signaling pathways in cancer cells without presenting any toxicity to normal cells.
It also inhibits migration and invasion of human cervical cancer cells. It can inhibit stages in the cancer cell, prevent cell cycle progression, inhibit cell growth and induce apoptosis.